Thorne ResveraCel®

Description

What it is:

 ResveraCel combines nicotinamide riboside with resveratrol and cofactors to support healthy aging.* It provides support for metabolic syndrome and increases cellular energy production.*

 

Key Benefits?

  • Supports healthy aging*
  • Betaine provides important methylation factors*
  • Resveratrol and quercetin increase activity of sirtuins*
  • Contains nicotinamide riboside (NR) – the most efficient direct precursor to NAD+*
  • Helps regulate metabolism for improved metabolic syndrome parameters*
  • Quercetin is bound to sunflower-sourced phospholipids for enhanced absorption.

 

The science behind ResveraCel:

Nicotinamide riboside (NR)

NR is the most direct precursor to nicotinamide adenine dinucleotide (NAD+). The mitochondria cannot perform their crucial cellular functions without a sufficient supply of NAD+.* By significantly increasing levels of NAD+, NR offers fundamental support for mitochondrial biogenesis, as well as all other mitochondrial activities – from energy production to the regulation of cellular aging.* Using an animal model, researchers found significant decreases in NAD+ by middle age, associated with increased oxidative stress and decreased SIRT1 levels.1*

NR provides support for metabolism.* NR prevented obesity in mice fed a high-fat, high-calorie diet.* It also prevented fat accumulation in the liver and improved insulin sensitivity and glucose disposal.* Other metabolic effects included improved thermogenesis, greater muscle endurance, and increased cristae density in brown adipose tissue.2*

Resveratrol

Calorie restriction has been shown to increase the lifespan of many species. Resveratrol mimics the effect of calorie restriction by activating the sirtuin group of proteins.* In a study, resveratrol was shown to be the most potent natural sirtuin activator.3* Resveratrol shows promise in helping to attenuate the effects of several age-related conditions.4*

Resveratrol increases activation of SIRT1 and SIRT3, both of which are important sirtuins in the maintenance of metabolic function.* In animals fed a high-calorie diet, resveratrol protected against obesity, improved metabolism, and supported insulin sensitivity.5* Resveratrol provides support for fatty liver,6* healthy blood pressure,7* and normal blood glucose levels.8*

 

The science behind ResveraCel® (cont.):

Quercetin phytosome

Research shows that quercetin not only acts as a potent antioxidant and is synergistic with the activities of resveratrol, it also slows the breakdown of resveratrol in the body.* Although resveratrol goes through extensive liver metabolism, researchers found quercetin inhibits duodenal and hepatic glucuronidation and sulfation of resveratrol, thus increasing its bioavailability.9,10*

Like resveratrol, quercetin also enhances sirtuin activity.11* A study in an animal model of metabolic syndrome found the combination of quercetin and resveratrol improved serum parameters associated with MetS by up-regulation of SIRT1 in white adipose tissue.12*

Quercetin has also been shown to provide support for fatty liver.13

Betaine

Betaine – also known as trimethylglycine – is a premier methyl donor.* In addition to providing significant methylation support because it can donate three methyl groups, betaine provides support for important metabolic functions that are associated with metabolic syndrome.* It helps metabolize homocysteine, which is sometimes elevated in MetS.14* Betaine has also been shown to decrease infiltration of triglycerides into the liver, providing nutritional support for fatty liver.15*

 

Suggested Use:

Take 2 capsules one to two times daily or as recommended by your health-care practitioner.
If pregnant, consult your health-care practitioner before using this product.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 

Additional information

Size

60 Capsules

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